Is the test reproducible?

Application to the paper: "Is it possible to exclude a diagnosis of myocardial damage within six hours of admission to an emergency department? Diagnostic cohort study" BMJ 2001;323:372(18 August)

Yes, the test is very reproducible. It has been well defined. There is very little inter-observer variability. Machines measure enzymes and ST segment changes.

But what about patient selection? It would seem that a large number of patients were excluded for various reasons and the criteria for exclusion are vague.

No signifance levels or confidence intervals were given.

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